These findings by Ophthalmos Research team support the use of omega-3 polyunsaturated fatty acids as a therapy for autosomal dominant optic atrophy.
Omega-3 fatty acid supplementation has neuroprotective effects on the retinas of a mouse model of OPA1-related autosomal dominant optic atrophy by blocking the inflammatory activation of astrocytes and microglia and by suppressing the proapoptotic Bcl-2-associated X protein and caspase-3 in the retinas.
https://www.sciencedirect.com/science/article/pii/S001448352100467X?dgcid=author